A 25 year old woman presents to the Emergency Department with a 2 day history of pain near her anus. She describes feeling an increasing swelling in the area. On examination you find a fluctuant area in the 3 o'clock perianal region with associated erythema. She is systemically well and has no past medical history. You see no evidence of fistulous disease. How should this patient be managed?
An anorectal abscess is an infection of the soft tissues around the anus. For patients with Crohn's disease, an anorectal abscess will develop in approximately one third of patients. Anorectal abscesses are between 2 and 3 times more common in men than women, with most abscesses occurring in patients between 20 to 40 years of age. Anorectal abscesses are associated with anal fistulas in 37% of patients. If these fistulas are not recognised and treated, perirectal abscesses may recur.
Anorectal abscesses are usually classified clinically, based on the anatomy of the abscess.
Anorectal abscess classification. (Image by McortNGHH (Own work) [CC BY-SA 4.0], via Wikimedia Commons)
The presence of key risk factors such as a history of Crohn's disease or anal fistula should be elicited. In addition, anorectal abscesses are more common in men than women.
Patients with anorectal abscesses usually relate a history of localised anal or perianal pain. Pain usually begins 1 to 2 days before presentation and becomes progressively more severe. Patients frequently complain of swelling and warmth of the perianal tissues. Fever is common and is usually <38.6ºC.
The most common finding on physical examination is a tender, indurated area immediately adjacent to the anus, within the anal canal, or above the anorectal ring.
Radiological studies are rarely helpful in the diagnosis and management of anorectal abscesses. Occasionally, for patients with complex or atypical presentations, or those with supralevator or horseshoe abscesses, anal ultrasonography has been used for evaluation. However, the severe pain associated with the anorectal abscess frequently limits the use of this modality. Other imaging modalities such as CT or MRI may be more helpful in the evaluation of these patients.
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Biochemistry | Normal Value |
---|---|
Sodium | 135 – 145 mmol/l |
Potassium | 3.0 – 4.5 mmol/l |
Urea | 2.5 – 7.5 mmol/l |
Glucose | 3.5 – 5.0 mmol/l |
Creatinine | 35 – 135 μmol/l |
Alanine Aminotransferase (ALT) | 5 – 35 U/l |
Gamma-glutamyl Transferase (GGT) | < 65 U/l |
Alkaline Phosphatase (ALP) | 30 – 135 U/l |
Aspartate Aminotransferase (AST) | < 40 U/l |
Total Protein | 60 – 80 g/l |
Albumin | 35 – 50 g/l |
Globulin | 2.4 – 3.5 g/dl |
Amylase | < 70 U/l |
Total Bilirubin | 3 – 17 μmol/l |
Calcium | 2.1 – 2.5 mmol/l |
Chloride | 95 – 105 mmol/l |
Phosphate | 0.8 – 1.4 mmol/l |
Haematology | Normal Value |
---|---|
Haemoglobin | 11.5 – 16.6 g/dl |
White Blood Cells | 4.0 – 11.0 x 109/l |
Platelets | 150 – 450 x 109/l |
MCV | 80 – 96 fl |
MCHC | 32 – 36 g/dl |
Neutrophils | 2.0 – 7.5 x 109/l |
Lymphocytes | 1.5 – 4.0 x 109/l |
Monocytes | 0.3 – 1.0 x 109/l |
Eosinophils | 0.1 – 0.5 x 109/l |
Basophils | < 0.2 x 109/l |
Reticulocytes | < 2% |
Haematocrit | 0.35 – 0.49 |
Red Cell Distribution Width | 11 – 15% |
Blood Gases | Normal Value |
---|---|
pH | 7.35 – 7.45 |
pO2 | 11 – 14 kPa |
pCO2 | 4.5 – 6.0 kPa |
Base Excess | -2 – +2 mmol/l |
Bicarbonate | 24 – 30 mmol/l |
Lactate | < 2 mmol/l |